Macugen is used to treat macular eye problems such as age-related macular degeneration. Age-related macular degeneration (AMD) is a disorder of retina which can cause blurring of vision or blindness.
Pegaptanib prevents leaking of blood vessels and also prevents new blood vessel formation in the eye. It is available in the solution form and only with your doctor’s prescription.
Before using Macugen, you must know all about the risks and complications associated with it.
Allergy
Inform your doctor if you are allergic to any food, preservatives, dyes, or had an allergic reaction when you used this drug before.
Children
There are no adequate studies done which prove Pegaptanib has harmful effects in children. However, safety and efficacy have not been established.
Elderly
This medicine does not cause any different side effects or problem than it does in younger adults.
Pregnancy
It is a category B drug. It is safe in pregnancy.
Breast Feeding
There are no adequate studies which prove that Pegaptanib passes into breast milk. If you are using Pegaptanib while nursing, discuss it with your doctor for possible risk factors.
Drug Interactions
Pegaptanib may interact with other drugs. Your doctor should be informed of any other medicines which you are taking. He may want to change the dosage or drug.
Other Medical Conditions
Several other conditions may reduce its effectiveness. Make sure you inform your doctor of conditions such as:
- Eye infection or
- Infection around the eye: Should not be used in patients with these conditions.
- Glaucoma
All medicines have some side effects. Make sure you meet with your doctor in using Macugen to avoid unwanted potential side effects.
Some people may experience none or minor side effects. Consult with your doctor if they become problematic or frequent.
More common are:
- Bladder pain
- Blindness
- Bloody eye
- Bloody or cloudy urine
- Blurred vision
- Burning, dry, or itching eyes
- Decreased vision or other changes in vision
- Difficult, burning, or painful urination
- Difficulty breathing
- Double vision
- Drainage from eyes
- Frequent urge to urinate
- Gradual loss of vision
- Halos around lights
- Itching of eyelid
- Looking through water
- Lower back or side pain
- Nausea
- Night blindness
- Over bright appearance of lights
- Painful irritation of the clear front part of the eye
- Redness, pain, swelling of eye, eyelid, or inner lining of eyelid
- Seeing flashes or sparks of light
- Seeing floating spots before the eyes
- Shortness of breath
- Sore eyes
- Swelling of the eye
- Tightness in chest
- Tunnel vision
- Vomiting
- Wheezing
Less common are:
- Feeling of constant movement of self or surroundings
- Flushed, dry skin
- Fruit-like breath odor
- Headache
- Hearing loss
- Inability to speak
- Increased hunger
- Numbness or tingling in face, arms, or legs
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.