Mitosol

Mitosol is an antimetabolite that is used in glaucoma surgery. This is to be administered only under a doctor’s supervision.

If you are about to start Mitosol, speak with your doctor about what you need to know. The risks and benefits the medicine offer must be weighed.

For Mitosol, you and your doctor must consider the following:

Allergies.

If you have any unusual reaction to any medicine, be sure to tell your doctor about it. Additionally, disclose other types of allergies - food, preservatives, animals, or dyes, if there are any. Read the package ingredients carefully and make sure you are not allergic to any of its ingredients.

Pediatric.

There are no appropriate studies performed to establish safety and efficacy of the use of this drug in children

Geriatric.

Studies show the use of topical mitomycin in the elderly does not cause geriatric-specific problems that may limit the usefulness of the drug.

Pregnancy.

This drug is not recommended for use in pregnant women or women planning to become pregnant. Studies show positive evidence of abnormalities in fetuses when used in pregnant women and animals.

Breastfeeding.

Although there are no adequate studies in lactating mothers that determine potential risk in an infant when breastfeeding, the benefits should be weighed against the risks before taking this medication.

Drug Interactions.

Some drugs have adverse effects when used together. Make sure to inform your doctor about other drugs you are taking, so that alterations and precautions will be made if necessary. Before using topical mitomycin, talk to your doctor about possible interactions if you are taking other medications.

It is also important to inform your doctor if you are smoking tobacco or drinking alcohol since these may interact with the drug’s effectiveness. Inform your doctor about any drug you are using,

Prescription or nonprescription, especially the following drugs:

• Rotavirus Vaccine, Live
• Adenovirus Vaccine Type 4, Live
• Adenovirus Vaccine Type 7, Live
• Bacillus of Calmette and Guerin Vaccine, Live
• Influenza Virus Vaccine, Live
• Measles Virus Vaccine, Live
• Mumps Virus Vaccine, Live Poliovirus Vaccine, Live
• Rubella Virus Vaccine, Live
• Smallpox Vaccine
• Tamoxifen
• Typhoid Vaccine
• Varicella Virus Vaccine
• Vinblastine
• Yellow Fever Vaccine

Other Medical Problems.

If you have other health problems, the use of this medicine may be affected. Inform your doctor if you have other medical conditions, especially hypotonia or cataracts, or you have had lens implant.

To use Mitosol properly, you must follow all instructions given by your doctor.

Mitosol eye solution must only be applied by your doctor or a trained health professional during glaucoma filtration surgery.

Before using Mitosol, there are some precautions you must take. Close monitoring is required while using this medicine.

Your doctor will check if the drug is working properly and decide whether the use of this medicine should be continued. Use a highly effective birth control to avoid pregnancy, as this medicine can harm your unborn baby.

If you think you got pregnant while on this treatment, talk to your doctor immediately. Consult your doctor if there are any signs of eye irritation, such as redness, itching, and swelling; these may mean you are allergic to the drug.

While not all people using Mitosol may suffer from these side effects, you may need to call your doctor if any of these are present:

• Blindness
• Changes in vision
• Dislocated eye implants
• Eye redness
• Eye pain
• Floaters in vision or flashes of light
• Veil or curtain appearing across part of vision
• Headache
• Irritation or inflammation of the eye
• Tearing of the eyes

While most of these side effects usually diminish as the body adjusts to the drug, calling your doctor may be needed. Some patients may experience side effects not listed above.

If your surgical wound opened, you have raised upper eyelid, or you are experiencing a sensitivity of the eyes to the light or a throbbing pain, consult your doctor immediately.