Hematologist-Oncologist Questions Factor V Leiden

Would Factor V Leiden make pregnancy high-risk?

I'm 24, and I was diagnosed with Factor V Leiden a few years ago after seeing how frequently I get blood clots. I want to start a family in the future, but I'm worried about any complications that can happen because of a pregnancy. Would this disorder make a pregnancy high-risk?

3 Answers

Yes, you are at risk of making blood clots and pregnancy due to hormonal changes makes the risk of blood clot formation even higher. However, if you are adequately anti-coagulated and under tight supervision, it should be okay. Nevertheless, it is high risk.
Yes. Pregnancy in of itself can increase the prevalence of VTE. That with a thrombophilia such as factor V Leyden would make it a high risk pregnancy.
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Hello,

The presence of Factor V Leiden would make a person have a higher risk of blood clots. Pregnancy itself, also increases the risk of blood clots compared to non-pregnant females. In this scenario, during pregnancy there can be a much higher risk of developing clots in the legs or the lungs, as well as pregnancy loss such as abortions.