Although only conducted on animals, there are studies that show promising results on the effects of fasting on the brain. According to these studies, the production of brain-derived neurotrophic factor (BDNF) is stimulated by fasting. An increased production of BDNF also increases the ability of the brain's neurons to withstand degeneration as well as enhance memory and learning.

An increase in the levels of BDNF also leads to increased levels of serotonin, which confirms the improved moods of aging men after having a two-day nutritional cleanse.

When it comes to guarding the body against aging, autophagy serves as a natural defense mechanism. Autophagy also plays a vital role when it comes to helping organ systems and other bodily processes to properly function, as well as in the repair of damaged cells for optimal cell function.

As people age, the role of autophagy is weakened or decreased, resulting in the body's diminished ability to repair itself. Fortunately, restricted calorie intake, fasting, and nutritional cleansing have shown to improve cellular repair and promote autophagy. For this reason, others claim that regular cleansing also has anti-aging benefits.