Hematologist-Oncologist Questions Hematologist-Oncologist

Is sickle cell disease genetically passed on?

I am a 31 year old female. I want to know sickle cell disease genetically passed on?

4 Answers

Yes, Sickle cell disease is a genetic condition that is present at birth. It is inherited in an autosomal recessive pattern meaning that the genes are in both parent as an autosomal recessive. The Sickle Cell Disease mutation is a mutation in both copies of a person’s HBB gene. This gene encodes for the component of hemoglobin, the oxygen-carrying protein in the red blood cell. Thank you.
Yes, sickle cell anemia is genetically passed on
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Yes, sickle cell trait and sickle cell disease are both inherited diseases.
Yes, it is passed on through chromosomes, equally from each parent. Two copies give you the disease, one copy, from one parent, gives you sickle cell trait. Trait has few but not zero symptoms, but two genes give you full-blown sickle cell disease. Need to see a hematologist and have a hemoglobin electrophoresis and a CBC done.