Dr. James A Decaprio MD
Oncologist | Medical Oncology
44 Binney St M457 Boston MA, 02115About
Dr. DeCaprio received his MD in 1984 from the University at Buffalo School of Medicine and Biomedical Sciences. He completed his internal medicine residency at the University of Chicago, and his medic ...
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site.
- The role of the J domain of SV40 large T in cellular transformation.
- pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppression.
- Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation.
- Loss of p19(ARF) eliminates the requirement for the pRB-binding motif in simian virus 40 large T antigen-mediated transformation.
- Phosphorylation of the retinoblastoma-related protein p130 in growth-arrested cells.
- Binding of SV40 large T antigen to the retinoblastoma susceptibility gene product and related proteins.
- HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression.
- Cellular transformation by SV40 large T antigen: interaction with host proteins.
- Nucleocytoplasmic shuttling of p130/RBL2: novel regulatory mechanism.
- Feedback regulation of the MBF transcription factor by cyclin Cig2.
- Enumeration of the simian virus 40 early region elements necessary for human cell transformation.
- Western blot screening for monoclonal antibodies against human separase.
- Processing, localization, and requirement of human separase for normal anaphase progression.
- Fludarabine-induced apoptosis of B chronic lymphocytic leukemia cells includes early cleavage of p27kip1 by caspases.
Awards
- Association of American Physicians
- 2004 Harvard University GSAS Everett Mendelsohn Excellence in Mentoring Aw
- 2002 Stohlman Scholar, Leukemia & Lymphoma Society
- 2000 Biological and Biochemical Sciences HMS Award in Teaching
- 1997 American Society for Clinical Investigation
Treatments
- Viral Oncology
Fellowships
- Dana-Farber Cancer Institute, Medical Oncology
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