Kevin O. Hicks M.D.
Doctor
113 Nationwide Dr Lynchburg VA, 24502About
Kevin O. Hicks M.D. is a top Doctor in Lynchburg, VA. With a passion for the field and an unwavering commitment to their specialty, Kevin O. Hicks M.D. is an expert in changing the lives of their patients for the better. Through their designated cause and expertise in the field, Kevin O. Hicks M.D. is a prime example of a true leader in health care. As a leader and expert in their field, Kevin O. Hicks M.D. is passionate about enhancing patient quality of life. They embody the values of communication, safety, and trust when dealing directly with patients. In Lynchburg, VA, Kevin O. Hicks M.D. is a true asset to their field and dedicated to the profession of medicine.
Education and Training
Virginia Commonwealth University / Medical College of Virginia School of Medic 1998
Virginia Commonwealth University School of Medicine 1998
Board Certification
RadiologyAmerican Board of RadiologyABR
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Measurement of extravascular drug diffusion in multicellular layers.
- Comparison of aromatic and tertiary amine N-oxides of acridine DNA intercalators as bioreductive drugs. Cytotoxicity, DNA binding, cellular uptake, and metabolism.
- Extravascular transport of the DNA intercalator and topoisomerase poison N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide (DACA): diffusion and metabolism in multicellular layers of tumor cells.
- Quantitation of bystander effects in nitroreductase suicide gene therapy using three-dimensional cell cultures.
- Multicellular resistance to tirapazamine is due to restricted extravascular transport: a pharmacokinetic/pharmacodynamic study in HT29 multicellular layer cultures.
- In vitro and in vivo models for evaluation of GDEPT: quantifying bystander killing in cell cultures and tumors.
- Oxygen dependence of the metabolic activation and cytotoxicity of tirapazamine: implications for extravascular transport and activity in tumors.
- Extravascular transport of drugs in tumor tissue: effect of lipophilicity on diffusion of tirapazamine analogues in multicellular layer cultures.
- Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs.
- Bystander effects of bioreductive drugs: potential for exploiting pathological tumor hypoxia with dinitrobenzamide mustards.
- Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104.
- Analysis of the hypoxia-activated dinitrobenzamide mustard phosphate pre-prodrug PR-104 and its alcohol metabolite PR-104A in plasma and tissues by liquid chromatography-mass spectrometry.
- Oxygen dependence and extravascular transport of hypoxia-activated prodrugs: comparison of the dinitrobenzamide mustard PR-104A and tirapazamine.
- Pharmacokinetic/pharmacodynamic model-guided identification of hypoxia-selective 1,2,4-benzotriazine 1,4-dioxides with antitumor activity: the role of extravascular transport.
- Hypoxia-selective 3-alkyl 1,2,4-benzotriazine 1,4-dioxides: the influence of hydrogen bond donors on extravascular transport and antitumor activity.
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