Cyclandelate (Oral Route)

Cyclandelate, a peripheral vasodilator, is used to improve blood circulation by increasing the size of blood vessels. It used to be available only with a prescription. Distribution was discontinued by Wyeth-Ayerst in April 1997. It was available in capsule form.

The pros and cons of using oral cyclandelate should be considered carefully before initiating treatment. This medication is contraindicated in patients who have had allergic reactions to similar drugs or any of its components. You should inform your physician also if you have allergies to food, dyes, animals, or other medicines.

Studies on the effects of oral cyclandelate on children have not been performed. This medication is expected to have similar effects on elderly patients as on younger adults although not enough research has been done on this particular age group.

There isn’t enough research regarding oral cyclandelate’s effects on the nursing baby. Consider your options carefully if you are lactating. Make sure the benefits outweigh the risks. Give your physician a complete medication list.

Cyclandelate can cause bad reactions if used concomitantly with certain medications. Also, ask your doctor if you need to avoid particular foods or beverages. This medication should be used with caution in people who have angina, bleeding problems, glaucoma, hardening of the arteries, recent heart attack, and recent stroke. Inform your doctor if you have these conditions or a history of them.

Follow your physician’s instructions regarding the dose, timing, and duration of treatment with oral cyclandelate. These depend on the severity of your condition and differ for each person. So do not change your dosage or timing and do not share your medication with someone else. This medication can be taken with food especially if it causes gastric irritation.

The recommended dosage for adults who have poor blood circulation is 1.2-1.6 g daily in divided doses. It should be taken before meals and before bedtime.

Your doctor may adjust the dosage and frequency depending on your response to treatment. He/she may lower it to 400-800 mg daily in 2-4 divided doses. Take a missed dose as soon as possible or when you remember to take it. However, skip it all together if it’s almost time for the next dose and resume your normal schedule.

Keep this medication away from the reach of children and away from moisture and direct sunlight. Discard medications that are expired or out of date. Again, do not share your medications with someone else.

You may not feel this medication’s therapeutic effects right away. Consult your primary care physician before deciding to stop taking the oral cyclandelate.

Abruptly discontinuing use may have unwanted side effects. Inform your doctor if you are a smoker because tobacco use can decrease the efficacy of this medicine.

Oral cyclandelate can cause you to become dizziness especially if you quickly get up from a sitting or lying position. You need to sit up or stand up slowly. Inform your healthcare provider if this does not improve or gets worse.

As your body adjusts to treatment, you may experience some side effects. These usually do not need medical treatment. You can also ask your healthcare provider for some tips on how to prevent these. However, if the side effects become bothersome or worse, check with your physician as soon as possible.

Minor side effects that are uncommon include:

• Heartburn
• Belching
• Stomach Pain
• Nausea
• Dizziness
• Increased heart rate
• Skin Flushing
• Sweating
• Headache
• Tingling Sensation in Face and Limbs
• or Weakness

If you experience effects that are not listed, inform your physician right away.