“What are the most natural looking dentures?”

Since every denture has the possibility of being different (or "natural"), it's completely dependent on the dentist and lab technician. The most natural dentures we ever made for a patient were dentures that didn't have perfectly aligned teeth. Having said that, there are a lot of patients who express the desire to have a natural-looking denture, but when that option was presented, many patients declined and opted for the perfectly-aligned denture (I've never had perfect teeth before so now's my chance"). Figure out what you want and make sure your dentist provides you with what's called the "try-in" appt for your denture, where you get to view the set up when it's been waxed-in and not processed in acrylic yet. That allows any changes to be made easily, whereas changes after the dentures are processed, require a total remake of the denture.