“positive ANA Antibodies and dsDNA ”
How likely is it that I have an autoimmune disorder with a positive ana antibodies test of 180 and a positive dsDNA test of 20? I also have low vitamin D and B12 . My C reactive protein is 12.2 . High Creatinine and urine 312.
Female | 34 years old
Complaint duration: 09/10/2022
Medications: None
Conditions: None
4 Answers
Hello, Unfortunately, you LIKELY DO HAVE DISEASE and NEED to see a Rheumatologist for evaluation. The ANA is common and many people with an ANA do not have disease. Most people with ds DNA do have disease. ds DNA goes with kidney disease and you have a high creatinine showing kidney problems. This means you NEED to find out what is going on in your kidney - the two specialists who can help are the Rheumatologist for what is autoimmune, and the Nephrologist for what is going on in your kidney. Please get checked out as soon as you can. v/r Dr Thomas Hoffmann
I am afraid that the answer is not as simple as one would like Every Rheumatologist needs to know what specific ANA test is performed at any laboratory that their patients use. And additionally, one needs to know the specifics of the anti-DNA assay as well. ANA is a screening test and it is very sensitive but not specific; That is why there are specific auto antibodies, termed, anti-DNA, anti-SSA and SSB, and anti-RNP/SM. In addition to the ANA test, it is important that the rheumatologist knows all of the signs and symptoms that the patient has been experiencing, as well as Details of the physical examination The presence of a strongly detected anti-DNA is very supportive of a possible diagnosis of systemic lupus erythematosus Elevation of serum creatinine coupled with an abnormal urinalysis and determination of protein spilling into urine can relate to the ANA and DNA results. Certain medications can cause drug induced, lupus and detection of positive ANA can be seen in such circumstances. Additionally, Hashimoto's thyroiditis is an inflammatory autoimmune condition of the thyroid that can be associated with positive ANA I would recommend that you follow up with your physician and determine whether Rheumatology consultation should be performed Get Outlook for iOS<https://aka.ms/o0ukef>
Depends on your symptoms, additional necessary lab results.
Lupus has multiple features including mouth and nasal sores, pleurisy, joint pains, fever, fatigue,low white count, etc. many people have positive lab tests like this after a covid vax or covid disease. Have your urine tested fro protein, and if negative you have little to worry about, but if it's positive ie out of range then see a rheumatologist.
