Avelox

1 What is Avelox?

Brand: Avelox

Generic: Moxifloxacin

Moxifloxacin is a quinolone antibiotic that is used to treat acute bacterial sinusitis, acute bacterial exacerbation of chronic bronchitis, community acquired pneumonia, uncomplicated skin and skin structure infections, complicated skin and skin structure infections, complicated intra-abdominal infections, and plague.

This product is available in tablet.

2 What to Know Before Using

Tell to your doctor if you are allergic to Moxifloxacin or to any other medications. You should also inform your healthcare providers if you are allergic to foods, dyes, or animals. Safety and effectiveness of this medication have not been established in children.

There are no specific problems that would limit the usefulness of Moxifloxacin in the elderly. However, elderly patients are prone to have undesirable side effects which may require medical attention.

Pregnancy category C – The use of Moxifloxacin during pregnancy is warranted only if benefits justify risks to the fetus and only when no alternative management is appropriate. There are no adequate studies whether Moxifloxacin can pass through breast milk or if it could cause harmful effects to the infant. Discuss with your doctor if you are breastfeeding a baby.

Taking this medicine with any of the following medicines is usually not recommended, but with exception in some cases. Dosage or frequency of one or both of your medicines may be changed if both medicines are prescribed together.

  • Amifampridine
  • Bepridil
  • Cisapride
  • Dronedarone
  • Mesoridazine
  • Pimozide
  • Piperaquine
  • Saquinavir
  • Sparfloxacin
  • Terfenadine
  • Thioridazine
  • Ziprasidone

Taking this medicine with any of the following medicines is usually not recommended, but with exception in some cases. Dosage or frequency of one or both of your medicines may be changed if both medicines are prescribed together.

  • Acarbose
  • Acetohexamide
  • Alfuzosin
  • Alogliptin
  • Amiodarone
  • Amitriptyline
  • Anagrelide
  • Apomorphine
  • Aripiprazole
  • Arsenic Trioxide
  • Asenapine
  • Astemizole
  • Atazanavir
  • Azithromycin
  • Bedaquiline
  • Benfluorex
  • Buserelin
  • Canagliflozin
  • Chloroquine
  • Chlorpromazine
  • Chlorpropamide
  • Ciprofloxacin
  • Citalopram
  • Clarithromycin
  • Clomipramine
  • Clozapine
  • Crizotinib
  • Cyclobenzaprine
  • Dabrafenib
  • Dapagliflozin
  • Dasatinib
  • Degarelix
  • Delamanid
  • Desipramine
  • Deslorelin
  • Disopyramide
  • Dofetilide
  • Dolasetron
  • Domperidone
  • Donepezil
  • Doxepin
  • Droperidol
  • Ebastine
  • Eribulin
  • Erythromycin
  • Escitalopram
  • Exenatide
  • Famotidine
  • Felbamate
  • Fingolimod
  • Flecainide
  • Fluconazole
  • Fluoxetine
  • Foscarnet
  • Fosphenytoin
  • Galantamine
  • Gatifloxacin
  • Gemifloxacin
  • Gliclazide
  • Glimepiride
  • Glipizide
  • Gliquidone
  • Glyburide
  • Gonadorelin
  • Goserelin
  • Granisetron
  • Halofantrine
  • Haloperidol
  • Histrelin
  • Hydroquinidine
  • Hydroxychloroquine
  • Ibutilide
  • Iloperidone
  • Imipramine
  • Insulin
  • Insulin Aspart, Recombinant
  • Insulin Bovine
  • Insulin Degludec
  • Insulin Detemir
  • Insulin Glulisine
  • Insulin Lispro, Recombinant
  • Itraconazole
  • Ivabradine
  • Ketoconazole
  • Lapatinib
  • Leuprolide
  • Levofloxacin
  • Linagliptin
  • Liraglutide
  • Lumefantrine
  • Mefloquine
  • Metformin
  • Methadone
  • Metronidazole
  • Mifepristone
  • Miglitol
  • Mizolastine
  • Nafarelin
  • Nateglinide
  • Nelfinavir
  • Nilotinib
  • Norfloxacin
  • Octreotide
  • Ofloxacin
  • Olanzapine
  • Ondansetron
  • Paliperidone
  • Panobinostat
  • Paroxetine
  • Pasireotide
  • Pazopanib
  • Pentamidine
  • Perflutren Lipid Microsphere
  • Perphenazine
  • Pioglitazone
  • Pipamperone
  • Posaconazole
  • Pramlintide
  • Probucol
  • Procainamide
  • Prochlorperazine
  • Promethazine
  • Propafenone
  • Protriptyline
  • Quetiapine
  • Quinidine
  • Quinine
  • Ranolazine
  • Rasagiline
  • Repaglinide
  • Rilpivirine
  • Risperidone
  • Ritonavir
  • Rosiglitazone
  • Saxagliptin
  • Sertindole
  • Sevoflurane
  • Sitagliptin
  • Sodium Phosphate
  • Sodium Phosphate, Dibasic
  • Sodium Phosphate, Monobasic
  • Solifenacin
  • Sorafenib
  • Sotalol
  • Sunitinib
  • Tacrolimus
  • Tamoxifen
  • Telaprevir
  • Telavancin
  • Telithromycin
  • Tetrabenazine
  • Tizanidine
  • Tolazamide
  • Tolbutamide
  • Tolterodine
  • Toremifene
  • Trazodone
  • Trimipramine
  • Triptorelin
  • Vandetanib
  • Vardenafil
  • Vemurafenib
  • Venlafaxine
  • Vildagliptin
  • Vinflunine
  • Voriconazole
  • Vorinostat
  • Warfarin

Taking this medicine with any of the following medications may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Dosage or frequency of one or both of your medicines may be changed if both medicines are prescribed together.

  • Aluminum Carbonate, Basic
  • Aluminum Hydroxide
  • Aluminum Phosphate
  • Betamethasone
  • Budesonide
  • Corticotropin
  • Cortisone
  • Cosyntropin
  • Deflazacort
  • Dexamethasone
  • Didanosine
  • DihydroxyaluminumAminoacetate
  • Dihydroxyaluminum Sodium Carbonate
  • Fludrocortisone
  • Fluocortolone
  • Hydrocortisone
  • Iron
  • Lanthanum Carbonate
  • Magaldrate
  • Magnesium Carbonate
  • Magnesium Hydroxide
  • Magnesium Oxide
  • Magnesium Trisilicate
  • Methylprednisolone
  • Prednisolone
  • Prednisone
  • Rifampin
  • Sucralfate
  • Triamcinolone
  • Zinc

Some medical conditions can interact with this medication. Tell your doctor if you have any of the following conditions:

3 Proper Usage

Follow your doctor's exact instructions on when and how to take this medication. Excessive use of medication is not recommended. This medicine should be taken with whole glass of water. Do not split, crush or chew it. This medicine may be taken with or without food.

If you are taking aluminum or magnesium-containing antacids, iron supplements, multivitamins, didanosine (Videx®), sucralfate (Carafate®), or zinc, take these medications at least 4 hours before or 8 hours after taking Moxifloxacin. Recommended dosage for adults is 400 milligrams once every 24 hours.

If you miss a dose of this medicine, take it as soon as possible. However, if it is near for your next dose, skip the missed dose and start again to your regular dosing schedule. Do not take a double dose to make up for a missed one.

Store the medication in a closed container at room temperature, away from heat, moisture, and direct light. Keep out of reach of children. Do not keep expired medications.

4 Precautions to Take

Check with your doctor right away if you have any of the following:

  • Low potassium levels in the blood. This medication may increase your risk of having a fast, slow or irregular heartbeat, loss of consciousness, or fainting spells.
  • Signs of allergic reaction while taking this medication.
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet. These may be symptoms of peripheral neuropathy.
  • Changes in the results of your blood or urine sugar tests. This medication may affect blood sugar levels.

Check with your doctor on regular visits to monitor your progress with the medication.

Moxifloxacin may cause diarrhea and it may occur 2 months or more after you stop taking this medicine. Check first with your doctor before taking any antidiarrheal medicine. Moxifloxacin may cause tendinitis or tearing of a tendon. This risk may be increased if you are over 60 years of age, are using steroid medicines, have severe kidney problems, have a history of tendon problems, or if you have received an organ transplant.

Check with your doctor right away if you have sudden pain or swelling in a tendon after exercise, bruise more easily after an injury, or are unable to bear weight or move the affected area. You should refrain from exercise until your doctor says otherwise.

This medicine may cause dizziness or drowsiness. Avoid driving, operating machineries, or any other unsafe activities when you take this medication. Avoid extensive sunlight exposure or wear protective clothing and apply sun screen before going outdoors since this medication may cause your skin to be more sensitive to sunlight.

Talk to your doctor if you are planning to take any other medication.

5 Potential Side Effects

If any of the following side effects occur, check with your doctor right away:

  • Abdominal or Stomach cramps
  • Abdominal or Stomach tenderness
  • Black, Tarry stools
  • Bleeding gums
  • Blisters
  • Bloating or Swelling of the face, arms, hands, lower legs, or feet
  • Blood in the urine or stools
  • Blurred vision
  • Bone pain
  • Burning, Crawling, Itching, Numbness, Prickling, "Pins and Needles", or Tingling feelings
  • Chest pain
  • Chills
  • Clay-colored stools
  • Cough
  • Crying
  • Dark urine
  • Diarrhea, watery and severe, which may also be bloody
  • Difficult or Labored breathing
  • Difficulty with moving
  • Difficulty with swallowing
  • Discouragement
  • Dizziness, Faintness, or Lightheadedness when getting up suddenly from a lying or sitting position
  • Dry mouth
  • Excessive muscle tone
  • Fainting
  • Fast, Irregular, Pounding, or Racing heartbeat or pulse
  • Feeling of unreality
  • Feeling of warmth or heat
  • Feeling sad or empty
  • Fever
  • Flushed, Dry skin
  • Flushing or Redness of the skin, especially on the face and neck
  • Fruit-like breath odor
  • Headache
  • Hyperventilation
  • Increased hunger
  • Increased sensitivity of the skin to sunlight
  • Increased thirst
  • Increased urination
  • Irregular heartbeat recurrent
  • Irritability
  • Joint pain, stiffness, or swelling
  • Lack of coordination
  • Loss of appetite
  • Loss of interest or pleasure
  • Lower back, side, or stomach pain
  • Mood or Mental changes
  • Muscle aching or cramping
  • Muscle pains or stiffness
  • Muscle tension or tightness
  • Nausea or Vomiting
  • Nervousness
  • Noisy breathing
  • Pain
  • Pain in the pelvis
  • Pain, Warmth, or Burning in the fingers, toes, and legs
  • Painful or Difficult urination
  • Painful, Swollen joints
  • Pale skin
  • Pinpoint red spots on the skin
  • Pounding in the ears
  • Problems with speech or speaking
  • Problems with vision or hearing
  • Quick to react or overreact emotionally
  • Rapid weight gain
  • Rapidly changing moods
  • Redness or Other discoloration of the skin
  • Restlessness
  • Seeing, Hearing, or Feeling things that are not there
  • Seizures
  • Sensation of the skin burning
  • Sense of detachment from self or body
  • Severe sunburn
  • Shakiness in the legs, arms, hands, or feet
  • Skin rash or itching
  • Sore throat
  • Sores, Ulcers, or White spots on the lips or in the mouth
  • Sweating
  • Swelling of the feet or lower legs
  • Swelling or Puffiness of the face
  • Swollen glands
  • Tightness in the chest
  • Tingling of the hands or feet
  • Tiredness
  • Trouble concentrating
  • Trouble sleeping
  • Troubled breathing with exertion
  • Unexplained weight loss
  • Unpleasant breath odor
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness
  • Unusual weight gain or loss
  • Vomiting of blood
  • Yellow eyes or skin
  • Blistering, Peeling, or Loosening of the skin
  • Burning, Numbness, Tingling, or Painful sensations
  • Change in the ability to see colors, especially blue or yellow
  • Difficulty with chewing or talking
  • Double vision
  • Drooping eyelids
  • Eye pain
  • General feeling of tiredness or weakness
  • Hives
  • Hoarseness
  • Irregular or Slow heart rate
  • Large, Hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • Light-colored stools
  • Muscle weakness
  • No blood pressure or pulse
  • Puffiness or Swelling of the eyelids or around the eyes, face, lips, or tongue
  • Red, Irritated eyes
  • Red skin lesions, often with a purple center
  • Severe headache
  • Severe tiredness
  • Stomach pain, continuing
  • Stopping of heart
  • Unconsciousness
  • Unsteadiness or Awkwardness
  • Unusual behavior, such as disorientation to time or place, failure to recognize people, hyperactivity, or restlessness
  • Weakness in the arms, hands, legs, or feet

There are also some side effects that do not need medical attention and can be resolved during treatment as your body adjusts to the medicine. You can discuss it to your doctor to give you an advice on how to prevent or reduce these side effects:

  • Acid or Sour stomach
  • Bad, Unusual, or Unpleasant (after) taste
  • Belching
  • Burning feeling in the chest or stomach
  • Change in sense of smell
  • Change in taste
  • Changes in vision
  • Continuing ringing or buzzing or other unexplained noise in the ears
  • Difficulty having a bowel movement (stool)
  • Excess air or gas in the stomach or intestines
  • Fear or Nervousness
  • Feeling of constant movement of self or surroundings
  • Full feeling
  • General feeling of discomfort or illness
  • Hearing loss
  • Heartburn
  • Impaired vision
  • Indigestion
  • Itching of the vagina or genital area
  • Lack or Loss of strength
  • Loss of memory
  • Pain during sexual intercourse
  • Passing of gas
  • Problems with memory
  • Redness, Swelling, or Soreness of the tongue
  • Sensation of spinning
  • Sleepiness or Unusual drowsiness
  • Sore mouth or tongue
  • Stomach discomfort, upset, or pain
  • Thick, White vaginal discharge with no odor or with a mild odor
  • White patches in the mouth or on the tongue

Not all side effects are listed above. If you notice any other effects, check with your healthcare professionals.

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