“About twin pregnancy ”

Need to see a specialist about that.

To tell you a little about Down's:

Diagnostic tests that can identify Down syndrome include: Chorionic villus sampling (CVS). In CVS, cells are taken from the placenta and used to analyze the fetal chromosomes. This test is typically performed in the first trimester, between 10 and 13 weeks of pregnancy.

Can you see Down syndrome in an ultrasound?

There are several options for Down syndrome prenatal screening. These include: A blood test and an ultrasound test during the first trimester of pregnancy. An ultrasound can detect fluid at the back of a fetus's neck, which sometimes indicates Down syndrome.

Screening tests

1. A blood test, done between 9 and 12 weeks into the pregnancy, looks for hormonal changes that can suggest there is a problem with the baby's chromosomes.

2. An ultrasound scan, done at 12 to 13 weeks into the pregnancy, measures the thickness of fluid behind the baby's neck, called the nuchal translucency.

*Folic Acid May Fight *Down Syndrome*. April 17, 2003 -- Taking folic acid supplements before and during early pregnancy may not only help prevent neural tube defects in babies, but it may also reduce the risk of Down syndrome.

Down syndrome is 50 percent. It is really hard to accept. The Anti-D becomes more and more indispensable, because of incompatibility maternal fetus, creating genetic malformation. My advice is to do a karyotype before the pregnancy.

Congratulations on your twin pregnancy. Anti D will be important if you are of Rhesus negative blood type. If you have A, B, AB, or O positive blood, then it won't be necessary. With Down syndrome, the risk gets higher with increasing age of the woman at the time of pregnancy, say, late 30s to 40s, but the blood test (MSST screening) is not diagnostic, and neither is the nuchal translucency ultrasound done at 11-12 weeks gestation. The only way to positively confirm Down syndrome is by doing 1 of 2 invasive procedures (amniocentesis or chronic villus sampling), both of which carry a risk of miscarriage. I wouldn't be quick to get a diagnostic test done or worry about your risks of having a Down syndrome child even if you're in the advanced maternal age category, unless there's a family history of Down syndrome. It'll be best to see the results of the next ultrasound at 18-20 weeks gestation, which will give a better clue if there are any organ dysfunctions. Be as happy and positive as you can be and take good care of yourself, as this will be protective for your twins in the womb.

Hi there. This is not my area of expertise and as far as I know, down is not related to ANTI-D injection at all. Please approach a gynecologist for more information.
Best wishes

For the anti D to be given it will be adviced only if you are Rh -ve and the baby isRh+ve so there is more information needed before the desicion is made. As for Down syndrome and the percentage in pregnancy, the percentage usually is very low when the female is in her early 20s and the percentage increases dramatically after the mother is over 35 years old. Again this is general guidelines and further informations are needed for more detailed answer

Hi, Firstly Anti D has no relationship with causing or preventing Downs syndrome. The percentage of Downs syndrome depends mainly on Maternal age, the higher the maternal age the higher the percentage. For example The risk at maternal age 25 is about 1/1000, by age 40 its roughly 1/60 and by age 49 it becomes 1/10. Also a previous History of downs syndrome baby will increase the risk in subsequent pregnancies. To find out Possibility of Downs syndrome a triple test or an NIPT blood test could be done to determine the likelihood. You can speak to your doctor in detail regarding these tests. I hope this gives you a bit of information.

Down syndrome continues to be the most common chromosomal disorder. Each year, about 6,000 babies are born with Down syndrome, which is about 1 in every 700 babies born (CDC report 2017). Screening tests, such as an ultrasound or a blood test during your first or second trimester can help show if the developing baby (fetus) is at risk for Down syndrome. But these tests sometimes give false-positive or false-negative results. Diagnostic tests, such as chorionic villus sampling or amniocentesis can show if a baby has Down syndrome. You may want to have these tests if you have abnormal results from a screening test or if you are worried about Down syndrome.

Anti-D (Rhogam) is given when the mother is Rh negative and had the potential exposure to Rh positive blood from the baby such as may occur during miscarriage, trauma, or delivery. So, if you are Rh negative and the fetus from your last miscarriage was Rh positive, then your doctor would give you Anti-D (Rhogam).