The Silent Threat of MASLD: How to Safeguard Your Liver Health

The Silent Threat of MASLD: How to Safeguard Your Liver Health

By Manoj K. Sharma, DO, Board Certified Internal Medicine — Elite Medical Associates

When most people think of liver disease, alcohol is the first culprit that comes to mind. But there’s another liver condition, affecting millions of people globally, that has nothing to do with alcohol: non-alcoholic fatty liver disease (NAFLD). Recently, however, we’ve begun using a more precise term to describe this condition—Metabolic dysfunction-associated steatotic liver disease, or MASLD. Why the change? Because MASLD is deeply rooted in metabolic health, and this name better reflects what we now understand about its causes. So, what is MASLD, how does it develop, and most importantly, how can you protect your liver health?

What is MASLD?

MASLD occurs when fat accumulates in the liver due to metabolic imbalances rather than alcohol consumption. What many people don’t realize is just how common this condition is—about 30% of people worldwide are affected. That makes MASLD one of the most prevalent chronic liver diseases, and if left unchecked, it can lead to more severe liver damage, including fibrosis (scarring), cirrhosis, and potentially even liver failure.

Dr. Arun Sanyal, a leading expert in liver diseases and a professor at Virginia Commonwealth University, points out that “MASLD is not just a liver disease—it’s a manifestation of metabolic dysfunction. It’s intricately linked with obesity, diabetes, and other metabolic disorders.” This connection is why managing MASLD involves more than just treating the liver—it requires a comprehensive approach to metabolic health.

Diagnosing MASLD: Understanding the Risks

Many patients come to us at Elite Medical Associates after being told they have a “fatty liver” during routine lab work or imaging studies. But fatty liver itself doesn’t tell the whole story. The key question is: has MASLD progressed to fibrosis, where the liver begins to scar? To answer that, we start by calculating something called the Fibrosis-4 (Fib4) score.

The Fib4 score is a simple calculation based on your age, liver enzymes (AST and ALT), and platelet count. If the score is high, it indicates a greater risk for liver fibrosis. In cases where fibrosis is suspected, we often use elastography, a non-invasive imaging technique, to assess liver stiffness. The stiffer the liver, the more advanced the fibrosis. To give you some context, a healthy liver usually measures around 5 kPa (kilopascals). If your elastography score starts creeping above 10 kPa, it’s a red flag for potential cirrhosis.

Why Fibrosis is the Game Changer

Fibrosis is a critical marker in determining a person’s long-term liver health. Dr. Sanyal explains, “If you’re developing fibrosis, your liver is in trouble. But the good news is that we can reverse fibrosis with the right interventions. Early diagnosis is key.”

At Elite Medical Associates, we focus on catching MASLD early and tracking fibrosis closely. Tools like elastography help us keep a close eye on liver health and guide our treatment plans accordingly.

The Path Forward: Treatment and Lifestyle Changes

So, what can be done if you’re diagnosed with MASLD? The answer often lies in lifestyle modifications. Studies have shown that losing just 5-10% of your body weight can significantly reduce liver fat, improve liver enzyme levels, and even reverse fibrosis. We always emphasize manageable, sustainable changes—small steps like cutting out sugary drinks, eating more fiber-rich vegetables, and choosing healthy snacks can have a significant impact.

In terms of medication, MASLD treatment is evolving rapidly. GLP-1 agonists, a class of drugs primarily used to manage diabetes, have shown promise in reducing liver fat and fibrosis. “GLP-1s represent a game changer in metabolic health,” says Dr. Kenneth Cusi, a leading researcher in the field of metabolic diseases. “These drugs don’t just help people lose weight—they also have a direct impact on reducing liver fat and inflammation.”

Emerging treatments like Resmetirom are also showing promise by specifically targeting liver fibrosis. We’re closely monitoring the development of new medications, such as dual GLP-1 and GIP receptor agonists, which have demonstrated even greater efficacy in clinical trials for reducing liver fat and fibrosis.

The Future of MASLD Management

As MASLD research continues to evolve, we are witnessing the dawn of a new era in liver health. New treatments are being tested, and medications that combine weight loss with liver protection are showing tremendous promise. At Elite Medical Associates, we are committed to staying at the forefront of this evolving landscape to provide the most effective treatments for our patients.

A Proactive Approach at Elite Medical Associates

At Elite Medical Associates, we believe that prevention is the best cure. Early diagnosis and intervention are the cornerstones of our approach to liver health. Whether you’ve been diagnosed with MASLD or have concerns about your liver, we offer comprehensive care, including the latest diagnostic tools, personalized lifestyle plans, and access to cutting-edge treatments.

We work closely with our patients to create manageable lifestyle changes that promote liver health and overall wellness. If medication is needed, we ensure you have access to the most effective options available. Remember, MASLD is a reflection of your metabolic health, so taking care of your liver means taking care of your whole body.

Conclusion

MASLD is a serious condition, but it is one we can manage and even reverse with early intervention, lifestyle changes, and the right treatments. If you’ve been told you have a fatty liver or are concerned about your liver health, we encourage you to take action today. At Elite Medical Associates, we’re here to guide you every step of the way.

Disclaimer: This article is for educational purposes only and should not be considered medical advice. Please consult your healthcare provider for personalized guidance and treatment options.

Contact Us: At Elite Medical Associates, we’re more than just a medical practice—we’re your dedicated partners in health. Whether you’re managing MASLD or simply seeking to optimize your overall well-being, we’re here to provide personalized, cutting-edge care tailored to your unique needs. Our team is committed to empowering you with the latest treatments, expert guidance, and compassionate support on your journey to a healthier, longer life.

Ready to take control of your liver health and beyond? Reach out to us today!

• Call/Text: 702-291-8511

• Email: info@EliteMedLV.com

• Website: EliteMedLV.com

At Elite Medical Associates, together, we can take proactive steps toward a healthier, brighter future. Let us be part of your journey to optimal health!