Rasagiline is used in treating Parkinson’s disease. This medicine can be used alone or together with Levodopa.
Parkinson's disease affects the nerve cells in the brain that produce dopamine. Its symptoms include muscle rigidity, tremors, and changes in speech and gait.
Tell to your doctor if you are allergic to Rasagiline or to any other medications. You should also inform your healthcare providers if you are allergic to foods, dyes, or animals.
Safety and effectiveness of this medicine have not been established in children. This medicine has not demonstrated geriatric-specific problems.
Pregnancy category C – The use of Rasagiline during pregnancy is warranted only if benefits justify risks to the fetus and only when no alternative management is appropriate.
This medicine inhibits prolactin secretion and may inhibit breast milk secretion. Monitor the infant for side effects and adequate milk intake if no alternative drug will be prescribed.
Taking Rasagiline with any of the following medicines is not recommended and you may not be required to receive this medication. Otherwise, alternative medicine may be prescribed for your other medications.
Taking this medicine with any of the following medicines is usually not recommended, but with exception in some cases. Dosage or frequency of one or both of your medicines may be changed if both medicines are prescribed together.
Taking this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Dosage or frequency of one or both of your medicines may be changed if both medicines are prescribed together.
Acarbose
Albiglutide
Alogliptin
Bromocriptine
Canagliflozin
Chlorpropamide
Dapagliflozin
Dulaglutide
Empagliflozin
Exenatide
Ginseng
Glimepiride
Glipizide
Glyburide
Insulin
Insulin Aspart, Recombinant
Insulin Bovine
Insulin Degludec
Insulin Detemir
Insulin Glulisine
Insulin Lispro, Recombinant
Linagliptin
Liraglutide
Lixisenatide
Metformin
Miglitol
Nateglinide
Pioglitazone
Pramlintide
Repaglinide
Rosiglitazone
Saxagliptin
Sitagliptin
Tolazamide
Tolbutamide
Vildagliptin
Some medical conditions can interact with this medication.
Tell your doctor if you have any of the following conditions:
Liver problems - should not be used in patients with this condition.
3 Proper Usage
Take Rasagiline exactly as prescribed by your doctor. Excessive use of this medication will increase the chance for side effects while inadequate use will not help your condition.
You may take this medicine with or without food.
Avoid consuming tyramine-rich foods and beverages while you are taking this medication. Doing so may cause you to experience hypertensive crisis or "cheese reaction". A hypertensive crisis is a severe increase in blood pressure that can lead to a stroke.
Here are the following tyramine-rich foods and beverages that you should avoid:
Aged cheese
Air dried, aged and fermented meats, sausages and salamis (eg, cacciatore, hard salami and mortadella)
Animal livers that are spoiled or improperly stored
Beers and tap beers, all varieties that have not been pasteurized so as to allow for ongoing fermentation
Broad bean pods (eg, fava bean pods)
Meat, poultry, or fish that is spoiled or stored improperly (eg, foods with changes in coloration, odor, or mold)
OTC supplements containing tyramine
Pickled herring
Red wine
Sauerkraut
Soybean products including soy sauce and tofu
Yeast extract, concentrated.
Recommended dosage for patients taking Rasagiline alone is 1 milligram once a day. For patients taking Rasagiline with Levodopa, starting dose is 0.5 milligram once a day. Your doctor may increase your dose up to 1 mg per day.
If you miss a dose of this medicine, take it as soon as possible. However, if it is near for your next dose, skip the missed dose and start again to your regular dosing schedule. Do not take a double dose to make up for a missed one.
Store the medication in a closed container at room temperature, away from heat, moisture, and direct light. Keep out of reach of children. Do not keep expired medications.
4 Precautions to Take
Your doctor will be checking you regularly for the effectiveness of the medication. Blood tests may be ordered as well for undesirable effects.
These could be symptoms of a serious condition called neuroleptic malignant syndrome.
You may experience increased dyskinesia if you take this medicine with levodopa. Check with your doctor if you have developed any of the following symptoms: twitching, twisting, uncontrolled repetitive movements of tongue, lips, face, arms, or legs.
This medicine can cause dizziness or drowsiness. Avoid driving, operating machineries, or any other risky activities when you take this medication.
This medicine will add to the effects of alcohol and other medicines that can make you drowsy or less alert. Check with your doctor before taking any of these medicines while you are using this medicine.
Discuss with your doctor if you have developed any unusual or strange thoughts and behaviour while receiving this medicine.
Slowly get up from a lying or sitting position since this medication may cause
Check with your doctor if this problem continues or gets worse.
Discuss first with your doctor if you are planning to stop taking this medication. Your doctor may want you to gradually reduce the amount you are taking before stopping completely.
Check with your doctor right away if you notice any unusual red, brown, or black spots on your skin, talk to your doctor right away. It is important that your doctor check your skin regularly for signs of a skin cancer called melanoma.
Talk to your doctor if you are planning to take any other medication. Rasagiline may cause a serious condition called serotonin syndrome when used with some medicines.
This especially includes medicines used to treat depression, such as
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